This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This protocol will create a specimen bank containing plasma, DNA and peripheral blood cells linked with relevant clinical information. This bank will support research that will improve the understanding of the normal range of human immunological phenotypes.